Peer Reviewed Open Access Journal
Volume 2 - Issue 1, January - February 2026
📑 Paper Information
| 📑 Paper Title | Clinical Evaluation of Individualized Homoeopathic Intervention in Alcohol Dependence: A Randomized Placebo-Controlled Study |
| 👤 Authors | Dr.Varun Puri, Dr.Pranab Kumar Chakarborty, Dr.Shalu Munjal |
| 📘 Published Issue | Volume 2 Issue 1 |
| 📅 Year of Publication | 2026 |
| 🆔 Unique Identification Number | IJAMRED-V2I1P230 |
| 📑 Search on Google | Click Here |
📝 Abstract
Background:
Alcohol dependence represents a chronic relapsing disorder with profound physical, psychological, and socioeconomic consequences. Despite the availability of pharmacological agents, challenges such as relapse, adverseeffects, and limited personalization necessitate exploration of complementary therapeutic strategies. Homoeopathy, based on individualized prescription principles, may offer a holistic alternative. The present study investigated the therapeutic impact of individualized Homoeopathic medicines on alcohol dependence severity using the Alcohol Use Disorders Identification Test (AUDIT).
Methods:
A randomized placebo-controlled clinical trial was conducted involving 100 screened individuals, of whom 84 fulfilled eligibility criteria. Participants were randomly allocated into two equal groups: individualized Homoeopathic treatment (n = 42) and placebo (n = 42). Prescriptions were formulated according to symptom totality, constitutional background, and repertorial evaluation. AUDIT scores were recorded at baseline and after a 3-month intervention period. Within-group and between-group comparisons were performed using paired t-tests and Welch’s independent t-test. Statistical significance was defined at p < 0.05.
Results:
Participants receiving individualized Homoeopathic therapy demonstrated a substantial decline in mean AUDIT scores from 29.4 to 20.1, reflecting a mean reduction of 9.26 ± 2.96 (t = 20.310; p < 0.001). Conversely, the placebo arm showed negligible change (29.1 to 28.9; mean difference 0.21 ± 1.37; t = 1.013; p = 0.317). Intergroup comparison revealed highly significant superiority of the Homoeopathy group (t = 17.997; p < 0.001), with a Cohen’s d of 3.93, indicating an exceptionally large effect magnitude.
Conclusion:
Individualized Homoeopathic management produced statistically and clinically meaningful reduction in alcohol dependence severity when compared to placebo. The magnitude of effect observed warrants further multicentric trials with extended follow-up.
Alcohol dependence represents a chronic relapsing disorder with profound physical, psychological, and socioeconomic consequences. Despite the availability of pharmacological agents, challenges such as relapse, adverseeffects, and limited personalization necessitate exploration of complementary therapeutic strategies. Homoeopathy, based on individualized prescription principles, may offer a holistic alternative. The present study investigated the therapeutic impact of individualized Homoeopathic medicines on alcohol dependence severity using the Alcohol Use Disorders Identification Test (AUDIT).
Methods:
A randomized placebo-controlled clinical trial was conducted involving 100 screened individuals, of whom 84 fulfilled eligibility criteria. Participants were randomly allocated into two equal groups: individualized Homoeopathic treatment (n = 42) and placebo (n = 42). Prescriptions were formulated according to symptom totality, constitutional background, and repertorial evaluation. AUDIT scores were recorded at baseline and after a 3-month intervention period. Within-group and between-group comparisons were performed using paired t-tests and Welch’s independent t-test. Statistical significance was defined at p < 0.05.
Results:
Participants receiving individualized Homoeopathic therapy demonstrated a substantial decline in mean AUDIT scores from 29.4 to 20.1, reflecting a mean reduction of 9.26 ± 2.96 (t = 20.310; p < 0.001). Conversely, the placebo arm showed negligible change (29.1 to 28.9; mean difference 0.21 ± 1.37; t = 1.013; p = 0.317). Intergroup comparison revealed highly significant superiority of the Homoeopathy group (t = 17.997; p < 0.001), with a Cohen’s d of 3.93, indicating an exceptionally large effect magnitude.
Conclusion:
Individualized Homoeopathic management produced statistically and clinically meaningful reduction in alcohol dependence severity when compared to placebo. The magnitude of effect observed warrants further multicentric trials with extended follow-up.
📝 How to Cite
Dr.Varun Puri, Dr.Pranab Kumar Chakarborty, Dr.Shalu Munjal,"Clinical Evaluation of Individualized Homoeopathic Intervention in Alcohol Dependence: A Randomized Placebo-Controlled Study" International Journal of Advanced Multidisciplinary Research and Educational Development, V2(1): Page(1467-1470) Jan-Feb 2026. ISSN: 3107-6513. www.ijamred.com. Published by Scientific and Academic Research Publishing.
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