Copper nanoparticles (CuNPs) were successfully synthesized using the aqueous extract of Syzygium cumini (Jamun) leaves through a green synthesis approach. The synthesized nanoparticles were characterized and evaluated for their biological activities. Antibacterial activity was assessed against both Gram-positive and Gram-negative bacteria using the agar well diffusion method. The antioxidant potential of nanoparticles was determined using DPPH radical scavenging assays, while their antidiabetic activity was evaluated through in vitro α-amylase and α-glucosidase inhibition assays. Results demonstrated that the biosynthesized CuNPs exhibited significant antibacterial, antioxidant, and antidiabetic properties, indicating their potential as a safe and eco-friendly bioactive material for pharmaceutical and biomedical applications. The study highlights the use of Jamun leaves as a sustainable and effective reducing and stabilizing agent in the green synthesis of copper nanoparticles.

Harshita Shekhawat, Shravani bagve, Hemangi Gehlot,"Antibacterial, Antioxidant and Antidaibetic Properties of Copper Nanoparticles synthesised using Syzygium Cumini Leaves" International Journal of Advanced Multidisciplinary Research and Educational Development, V2(4): Page(1779-1785) March - April 2026. ISSN: 3107-6513. www.ijamred.com. Published by Scientific and Academic Research Publishing.