Volume 2 - Issue 3, May - June 2026

Skin infections and minor wounds are common health concerns that often require topical antimicrobial treatment. Conventional antiseptic creams may cause adverse effects such as irritation, dryness, and allergic reactions following prolonged use. The present study aimed to formulate and evaluate a herbal antiseptic cream containing extracts of Tridax procumbens and Clitoria ternatea (Butterfly Pea), both of which possess well-documented antimicrobial, antioxidant, anti-inflammatory, and wound-healing properties. Plant materials were collected, shade-dried, powdered, and extracted by the decoction method. The obtained extracts were incorporated into an oil-in-water cream base containing cocoa butter, stearic acid, liquid paraffin, glycerin, borax, rose water, methyl paraben, and vitamin E. Three formulations (F1–F3) were prepared and evaluated for physicochemical parameters including appearance, pH, viscosity, spreadability, homogeneity, washability, stability, and skin irritation potential. The optimized formulation exhibited a smooth texture, acceptable pH (6.5), good spreadability, satisfactory viscosity, and excellent stability without evidence of irritation. The findings suggest that the developed herbal antiseptic cream may serve as a safe, effective, and economical topical preparation for the prevention of minor skin infections and promotion of wound healing.

Mohini Chaudhari, Gautami Ahire, Sakshi V. Kadale,"Formulation and Evaluation of Anti- Septic Cream Using By Tridax Procumbens and Butterfly Pea" International Journal of Advanced Multidisciplinary Research and Educational Development, V2(3): Page(972-978) May-June 2026. ISSN: 3107-6513. www.ijamred.com. Published by Scientific and Academic Research Publishing.